구분

내용

논문명

Safety Monitoring after the BNT162b2 COVID-19 Vaccine among Adul*s Aged 75 Years or Older

저자정보

Youn Young Choi, Min-Kyung Kim, Hyeok Choon Kwon, Gunn Hee Kim

학술지명

Journal of Korean Medical Science

개요

In total, 2,123 older adul*s received at least one vaccine dose during the study period. The frequency of acute adverse reactions that developed during the obser ved 15–30minutes after injection was 8.5 cases per 1,000 doses. None of the reactions was assessed

as acute allergic reactions to the vaccine and no cases required special treatment or drug administration. Overall, 638 people were followed up at least once by telephone inter view 7days post vaccination. The overall response rate was 82.3%. The rates of local reactions were 50.3% after the first dose and 45.2% after the second dose, and the rates of systemic reactions were 15.2% and 26.0%, respectively. During the study period, 23 medically attended adverse events (5.4 cases per 1,000 administered doses) were reported to the KDCA AEFI sur veillance system. The most common symptoms of medically attended cases were nonspecific general weakness (26%) and dizziness (26%), followed by muscle pain (22%), headache (13%), fever (13%), and skin rash or urticaria (13%). Among them, there were five serious adverse events reported, which required hospitalization, including one death. However, most of them were not related to the vaccines.

과제정보

[I_2021_002] 75세 이상 노인에서 코로나19 백신 예방접종 후 발생한 이상반응