구분

내용

논문명

Antibody Responses to SARS-CoV-2 in Children With COVID-19

저자정보

Mi Seon Han, Jihye Um, Eun Joo Lee, Kyung Min Kim, Sung Hee Chang, Hyunju Lee, Ye Kyung Kim, Youn Young Choi, Eun Young Cho, Dong Hyun Kim, Jae Hong Choi, Jina Lee, Misuk Kim, Ki-Hyun Chung, Hye Sook Min, Young June Choe, Dong-Gyun Lim, Jun-Sun Park, Eun Hwa Choi

학술지명

Journal of the Pediatric Infectious Diseases Society

개요

One hundred sixty-five blood samples from 114 children with COVID-19 (43.9% asymptomatic and 56.1% mildly symptomatic) were analyzed. In both asymptomatic and mildly symptomatic children, the positive rates of anti-S IgG, anti-SARSꠓCoV-2 IgG, and NAb were low within 7 days after onset, but they soon reached 100% 14 to <28 days after onset. In symptomatic children, the geometric mean titers (GMTs) of antibodies were all below the positive cutoff during the first 2 weeks from onset and peaked at 28 to <56 days (5.6 for anti-S IgG, 383.6 for anti-SARS-CoV-2 IgG, and 55.0 for NAb, P < .001, respectively). Antibody levels remained detectable up to 3 months after infection. The antibody GMTs during the period 14 to <56 days after symptom onset were highest in children aged 0-4 years.

과제정보

[O_2020_006] 지역 보건의료통계 강화방안-응급의료 영역을 중심으로